Drug-induced Bullous Pemphigoid with Positive Patch Test and in vitro IgE Sensitization

Drug-induced bullous pemphigoid with positive patch test and in vitro IgE sensitization.

Sir, Bullous pemphigoid (BP) is a relatively common autoimmune skin disease characterized by blister formation, eosinophilia, chronicity and a relatively old age of onset (1). Drugs, including penicillin (2), may trigger BP, but this is a far less common event than drug-induced pemphigus vulgaris (1). The literature describes no clinical or laboratory features that distinguish idiopathic and dr...

Trauma-induced bullous pemphigoid

Indian J Dermatol Venereol Leprol | November-December 2009 | Vol 75 | Issue 6 Both ELISA and WB results were consistent for different storage periods (up to 10 days), suggesting that antibodies from sera collected on filter paper can remain stable. Stability of antibodies reactive to viral antigens of diagnostic importance was further tested with two of these samples for a 15-days storage perio...

Carbamazepine-induced bullous eruption or bullous pemphigoid?

Does drug-induced hypersensitivity syndrome elicit bullous pemphigoid?

Mefenamic acid-induced bullous pemphigoid.

A 52 year old man developed bullous pemphigoid, Coombs' positive haemolytic anaemia and diarrhoea related to the use of mefenamic acid. Clinical manifestation of the bullous pemphigoid, haemolytic anaemia and diarrhoea resolved following discontinuation of the mefenamic acid. Mefenamic acid should be added to the list of agents that are known to induce bullous pemphigoid.